TY - JOUR
T1 - The effects of prenatal chlordiazepoxide administration on avoidance behavior and benzodiazepine receptor density in adult albino rats
AU - Avnimelech-Gigus, N.
AU - Feldon, J.
AU - Tanne, Z.
AU - Gavish, M.
PY - 1986/9/23
Y1 - 1986/9/23
N2 - Adult male and female offspring of rats injected daily with 10 mg/kg chlordiazepoxide during their pregnancy exhibited a facilitated acquisition of a two-way active avoidance response. Benzodiazepine receptor assays carried out on cortex and cerebral samples taken from experimental and control female rats showed a significant decrease in the density of benzodiazepine receptors, without changes in receptor affinity.
AB - Adult male and female offspring of rats injected daily with 10 mg/kg chlordiazepoxide during their pregnancy exhibited a facilitated acquisition of a two-way active avoidance response. Benzodiazepine receptor assays carried out on cortex and cerebral samples taken from experimental and control female rats showed a significant decrease in the density of benzodiazepine receptors, without changes in receptor affinity.
KW - (Rat)
KW - Avoidance behavior
KW - Benzodiazepine receptors
KW - Chlordiazepoxide
KW - Prenatal administration
UR - http://www.scopus.com/inward/record.url?scp=0022909023&partnerID=8YFLogxK
U2 - 10.1016/0014-2999(86)90352-3
DO - 10.1016/0014-2999(86)90352-3
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AN - SCOPUS:0022909023
SN - 0014-2999
VL - 129
SP - 185
EP - 188
JO - European Journal of Pharmacology
JF - European Journal of Pharmacology
IS - 1-2
ER -