Abstract
Cheng and Brunner recently proposed a GABA hypothesis for the mechanism of action of anaesthetic agents. They presented evidence suggesting that halothane produces a state of anaesthesia by modifying CNS GABA-ergic transmission. Benzodiazepines (BZ), on the other hand, are known to modulate GABA-ergic transmission by binding to the benzodiazepine receptors (BZR). The following studies were designed in order to test the hypothesis that the specific BZR antagonist flumazenil interacts with halothane anaesthesia to hasten recovery.
| Original language | English |
|---|---|
| Pages (from-to) | 151-153 |
| Number of pages | 3 |
| Journal | European Journal of Anaesthesiology |
| Volume | 5 |
| Issue number | SUPPL. 2 |
| State | Published - 1988 |
| Externally published | Yes |