The effect of water deprivation and hypertonic salt injection on the oxygen consumption and plasma NaCl concentration in the albino rat

Uri Katz, Arieh Borut, Yosef Sarne

Research output: Contribution to journalArticlepeer-review

Abstract

O2-consumption of the whole animal was measured for rats deprived of water and food, or food only, at 27°C (for 3 days), 35°C (for 1 day), and in animals injected with NaCl solution intraperitoneally (3 ml/100 g B. W. of 3% NaCl). O2-consumption calculated per gram body weight, decreased by about 20% compared with the control value in animals deprived of water at 27°C, but increased by about 9% in animals deprived of water at 35° C. A 15% to 40% increase in the O2-consumption over the control value was found in the salt injected animals. Plasma NaCl concentration increased by about 5% and 10% in the animals deprived of water at 27°C and 35°C respectively; an increase of about 10% was found in the salt injected group. Rectal temperature was not affected by the experimental treatments. It is suggested that the reduction of the extracellular fluid volume for a long period might explain the observed reduction in the O2-consumption for the animals deprived of water at 27°C.

Original languageEnglish
Pages (from-to)69-77
Number of pages9
JournalPflugers Archiv European Journal of Physiology
Volume339
Issue number1
DOIs
StatePublished - Mar 1973
Externally publishedYes

Keywords

  • Albino Rat
  • Hypertonic Salt Injection
  • O-Consumption
  • Plasma NaCl Concentration
  • Rectal Temperature
  • Water Deprivation

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