The effect of trihexphenidyl (artane) on memory in schizophrenic patients

Shmuel Fennig; Yosi Levine; Silvana Naisberg; Avner Elizur

doi:10.1016/0278-5846(87)90033-9

The effect of trihexphenidyl (artane) on memory in schizophrenic patients

Shmuel Fennig^*, Yosi Levine, Silvana Naisberg, Avner Elizur

^*Corresponding author for this work

Clinical Departments

Shalvata Mental Health Center

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Shmuel Fennig, Yosi Levine, Silvana Naisberg and Avner Elizur: The Effect of Trihexphenidyl (Artane) on Memory in Schizophrenic Patients. Prog. Neuro-Psychopharmacol. and Biol. Psychiat. 1987, 11: 71-78. 1. 1. The anticholinergic effect of trihexphenidyl on memory function of 20 schizophrenic patients has been investigated in a double blind cross-over design. 2. 2. Impairment of immediate memory and short term memory was evident after trihexphenidyl treatment in comparison with placebo. Sensory short term memory tested by visual tasks and remote memory showed no significant statistical differences. 3. 3. Our data suggested that trihexphenidyl due to its anticholinergic effect might impair memory function.

Original language	English
Pages (from-to)	71-78
Number of pages	8
Journal	Progress in Neuro-Psychopharmacology and Biological Psychiatry
Volume	11
Issue number	1
DOIs	https://doi.org/10.1016/0278-5846(87)90033-9
State	Published - 1987

Keywords

anticholinergic effect
memory function
trihexphenidyl

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10.1016/0278-5846(87)90033-9

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abstract = "Shmuel Fennig, Yosi Levine, Silvana Naisberg and Avner Elizur: The Effect of Trihexphenidyl (Artane) on Memory in Schizophrenic Patients. Prog. Neuro-Psychopharmacol. and Biol. Psychiat. 1987, 11: 71-78. 1. 1. The anticholinergic effect of trihexphenidyl on memory function of 20 schizophrenic patients has been investigated in a double blind cross-over design. 2. 2. Impairment of immediate memory and short term memory was evident after trihexphenidyl treatment in comparison with placebo. Sensory short term memory tested by visual tasks and remote memory showed no significant statistical differences. 3. 3. Our data suggested that trihexphenidyl due to its anticholinergic effect might impair memory function.",

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The effect of trihexphenidyl (artane) on memory in schizophrenic patients

Abstract

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