The Effect of Rapid Digitalization on Ventricular Function in Patients With Congestive Heart Failure

Zvi Rotenberg, Chaim Hellman, Itzhak Weinberger, Jacob Fuchs, Jacob Agmon

Research output: Contribution to journalArticlepeer-review

Abstract

Cardiac glycosides have been used in the treatment of cardiac failure for more than 200 years. Digitalis and its analogues have been shown to increase myocardial contractility and to decrease left ventricular end‐diastolic pressure and volume, while causing no essential change in aortic pressure and a variable decrease in heart rate.1–2 However, several reports3–8 have questioned the use of digitalis in patients with ventricular dysfunction, particularly in view of the newer modes of therapy. The aim of this study was to define the effects of rapid digitalization on left and right ventricular function in patients with chronic congestive heart failure, using radionuclide methods. 1985 American College of Clinical Pharmacology

Original languageEnglish
Pages (from-to)384-386
Number of pages3
JournalJournal of Clinical Pharmacology
Volume25
Issue number5
DOIs
StatePublished - 1985
Externally publishedYes

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