The effect of prostaglandins and aspirin-an inhibitor of prostaglandin synthesis-on adhesion formation in rats

A. Golan*, T. Bernstein, S. Wexler, M. Neuman, I. Bukovsky, M. P. David

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The effect of Intrapentoneal application of prostaglandins E2 and F and of aspirin, a non-steroidal anti-inflanunatory drug, on the formation of intrapentoneal adhesions was investigated in rats, in view of the main role of the body's reaction in adhesion formation. hitraperitoneal adhesions were induced by inflicting uniform trauma to the uterine serosa. It was demonstrated that prostaglandin E2 may increase adhesion formation and that intrapentoneal aspirin is able to Inhibit its formation.

Original languageEnglish
Pages (from-to)251-254
Number of pages4
JournalHuman Reproduction
Volume6
Issue number2
DOIs
StatePublished - Feb 1991

Keywords

  • Adhesion formation
  • Aspirin
  • Prostaglandins

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