The effect of Intrapentoneal application of prostaglandins E2 and F2α and of aspirin, a non-steroidal anti-inflanunatory drug, on the formation of intrapentoneal adhesions was investigated in rats, in view of the main role of the body's reaction in adhesion formation. hitraperitoneal adhesions were induced by inflicting uniform trauma to the uterine serosa. It was demonstrated that prostaglandin E2 may increase adhesion formation and that intrapentoneal aspirin is able to Inhibit its formation.
Number of pages|
Published - Feb 1991|