@article{213477502fe54d8b89f1f62838a856e4,
title = "The effect of pressure on the excited-state proton transfer in the wild-type green fluorescent protein",
abstract = "Ultrahigh-pressure dependence of the excited-state proton transfer (ESPT) in the wild-type green fluorescence protein (wt-GFP) in D2O was measured using steady-state and picosecond time-resolved fluorescence spectroscopies. The proton dissociation rate of the chromophore is almost insensitive to a pressure increase up to about 1.1 GPa. In contrast, the diffusion-limited geminate recombination kinetics is strongly affected by pressure, decreasing the effective dimensionality of proton diffusion as pressure increased. The GFP β-barrel structure sustains the high pressure and unfolds only at P > 1.5 GPa.",
author = "Pavel Leiderman and Dan Huppert and Remington, \{S. James\} and Tolbert, \{Laren M.\} and Solntsev, \{Kyril M.\}",
note = "Funding Information: This work was supported by grants from the Binational US-Israel Science Foundation (for D.H., S.J.R., and L.M.T.), the US National Science Foundation (CHE-0456892 for L.M.T. and K.M.S.), and the James-Franck German–Israel Program in Laser-Matter Interactions for D.H.",
year = "2008",
month = apr,
day = "10",
doi = "10.1016/j.cplett.2008.02.079",
language = "אנגלית",
volume = "455",
pages = "303--306",
journal = "Chemical Physics Letters",
issn = "0009-2614",
publisher = "Elsevier B.V.",
number = "4-6",
}