The effect of parathyroid hormone (PTH) and 1,25 dihydroxy vitamin D3 (1,25(OH)2D3) on RNA and heme synthesis by erythroid precursors.

J. Levi*, D. Zevin, H. Bessler, M. Djaldetti

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

PTH was shown to stimulate RNA and heme synthesis in 12-13 days embryonic mouse liver erythroid cells, thus expressing an erythropoietin-like effect. Incubation of erythroid precursors with 1,25(OH)2D3 had no effect on heme synthesis, and increased the RNA synthesis only slightly, thus showing no enhancement effect of 1,25(OH)2D3 on the PTH stimulating effect on erythropoiesis.

Original languageEnglish
Pages (from-to)603-607
Number of pages5
JournalProceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association
Volume17
StatePublished - 1980

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