The effect of nasolacrimal occlusion on drug-induced mydriasis

Anat Loewenstein*, Alon Sadeh, Michaella Goldstein, Moshe Lazar

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


• Background: Nasolacrimal occlusion has been shown to improve the efficacy of some topically applied ocular drugs. The aim of this study was to investigate the effect of nasolacrimal occlusion on tropicamide-induced mydriasis. • Methods: We compared pupillary dilatation by 0.125% tropicamide with and without nasolacrimal occlusion in 40 healthy volunteers. • Results: Analysis of variance with repeated measures failed to show any advantage due to nasolacrimal occlusion in drug-induced mydriasis. • Conclusion: Nasolacrimal occlusion did not increase the mydriasis obtained with 0.125% tropicamide.

Original languageEnglish
Pages (from-to)530-531
Number of pages2
JournalGraefe's Archive for Clinical and Experimental Ophthalmology
Issue number8
StatePublished - Aug 1995
Externally publishedYes


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