The effect of medical versus surgical treatment of spontaneous miscarriage on subsequent in vitro fertilization cycles

Rina Tamir, Sarit Allouche, Ariel Weissman, Einat Haikin Herzberger, Suzi Oberman-Farhi, Einat Shalom-Paz, Adrian Shulman, Amir Wiser

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To evaluate the effect of dilation and curettage (D&C) and misoprostol as treatments for spontaneous miscarriage (SM) on in vitro fertilization (IVF) parameters in the subsequent IVF cycle. Design: Multicenter, retrospective, cohort study. Women treated for SM after IVF treatment with D&C or misoprostol and underwent a subsequent IVF cycle was included. The main outcome measures were ovarian response, endometrial thickness and pregnancy rate in the subsequent IVF cycle after MA. Results: Among 73 patients with miscarriage, 41 had D&C and 32 were given misoprostol. Baseline serum follicle stimulating hormone (FSH) levels and ovarian responses before and after treatment of miscarriage were comparable. No significant differences were observed between the D&C and the misoprostol groups in basal FSH levels, endometrial thickness and parameters of ovarian response in the subsequent IVF cycle. Conclusion: D&C and misoprostol are both effective treatments for IVF patients with miscarriage, without an adverse effect on subsequent IVF treatment outcome.

Original languageEnglish
Pages (from-to)231-233
Number of pages3
JournalGynecological Endocrinology
Volume32
Issue number3
DOIs
StatePublished - 3 Mar 2016

Keywords

  • D&C
  • IVF
  • lag period
  • miscarriage
  • misoprostol

Fingerprint

Dive into the research topics of 'The effect of medical versus surgical treatment of spontaneous miscarriage on subsequent in vitro fertilization cycles'. Together they form a unique fingerprint.

Cite this