The effect of medical versus surgical treatment of spontaneous miscarriage on subsequent in vitro fertilization cycles

Rina Tamir; Sarit Allouche; Ariel Weissman; Einat Haikin Herzberger; Suzi Oberman-Farhi; Einat Shalom-Paz; Adrian Shulman; Amir Wiser

doi:10.3109/09513590.2015.1110693

The effect of medical versus surgical treatment of spontaneous miscarriage on subsequent in vitro fertilization cycles

Rina Tamir, Sarit Allouche, Ariel Weissman, Einat Haikin Herzberger, Suzi Oberman-Farhi, Einat Shalom-Paz, Adrian Shulman, Amir Wiser^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Objective: To evaluate the effect of dilation and curettage (D&C) and misoprostol as treatments for spontaneous miscarriage (SM) on in vitro fertilization (IVF) parameters in the subsequent IVF cycle. Design: Multicenter, retrospective, cohort study. Women treated for SM after IVF treatment with D&C or misoprostol and underwent a subsequent IVF cycle was included. The main outcome measures were ovarian response, endometrial thickness and pregnancy rate in the subsequent IVF cycle after MA. Results: Among 73 patients with miscarriage, 41 had D&C and 32 were given misoprostol. Baseline serum follicle stimulating hormone (FSH) levels and ovarian responses before and after treatment of miscarriage were comparable. No significant differences were observed between the D&C and the misoprostol groups in basal FSH levels, endometrial thickness and parameters of ovarian response in the subsequent IVF cycle. Conclusion: D&C and misoprostol are both effective treatments for IVF patients with miscarriage, without an adverse effect on subsequent IVF treatment outcome.

Original language	English
Pages (from-to)	231-233
Number of pages	3
Journal	Gynecological Endocrinology
Volume	32
Issue number	3
DOIs	https://doi.org/10.3109/09513590.2015.1110693
State	Published - 3 Mar 2016

Keywords

D&C
IVF
lag period
miscarriage
misoprostol

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10.3109/09513590.2015.1110693

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title = "The effect of medical versus surgical treatment of spontaneous miscarriage on subsequent in vitro fertilization cycles",

abstract = "Objective: To evaluate the effect of dilation and curettage (D&C) and misoprostol as treatments for spontaneous miscarriage (SM) on in vitro fertilization (IVF) parameters in the subsequent IVF cycle. Design: Multicenter, retrospective, cohort study. Women treated for SM after IVF treatment with D&C or misoprostol and underwent a subsequent IVF cycle was included. The main outcome measures were ovarian response, endometrial thickness and pregnancy rate in the subsequent IVF cycle after MA. Results: Among 73 patients with miscarriage, 41 had D&C and 32 were given misoprostol. Baseline serum follicle stimulating hormone (FSH) levels and ovarian responses before and after treatment of miscarriage were comparable. No significant differences were observed between the D&C and the misoprostol groups in basal FSH levels, endometrial thickness and parameters of ovarian response in the subsequent IVF cycle. Conclusion: D&C and misoprostol are both effective treatments for IVF patients with miscarriage, without an adverse effect on subsequent IVF treatment outcome.",

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author = "Rina Tamir and Sarit Allouche and Ariel Weissman and {Haikin Herzberger}, Einat and Suzi Oberman-Farhi and Einat Shalom-Paz and Adrian Shulman and Amir Wiser",

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doi = "10.3109/09513590.2015.1110693",

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AU - Oberman-Farhi, Suzi

AU - Shalom-Paz, Einat

AU - Shulman, Adrian

AU - Wiser, Amir

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N2 - Objective: To evaluate the effect of dilation and curettage (D&C) and misoprostol as treatments for spontaneous miscarriage (SM) on in vitro fertilization (IVF) parameters in the subsequent IVF cycle. Design: Multicenter, retrospective, cohort study. Women treated for SM after IVF treatment with D&C or misoprostol and underwent a subsequent IVF cycle was included. The main outcome measures were ovarian response, endometrial thickness and pregnancy rate in the subsequent IVF cycle after MA. Results: Among 73 patients with miscarriage, 41 had D&C and 32 were given misoprostol. Baseline serum follicle stimulating hormone (FSH) levels and ovarian responses before and after treatment of miscarriage were comparable. No significant differences were observed between the D&C and the misoprostol groups in basal FSH levels, endometrial thickness and parameters of ovarian response in the subsequent IVF cycle. Conclusion: D&C and misoprostol are both effective treatments for IVF patients with miscarriage, without an adverse effect on subsequent IVF treatment outcome.

AB - Objective: To evaluate the effect of dilation and curettage (D&C) and misoprostol as treatments for spontaneous miscarriage (SM) on in vitro fertilization (IVF) parameters in the subsequent IVF cycle. Design: Multicenter, retrospective, cohort study. Women treated for SM after IVF treatment with D&C or misoprostol and underwent a subsequent IVF cycle was included. The main outcome measures were ovarian response, endometrial thickness and pregnancy rate in the subsequent IVF cycle after MA. Results: Among 73 patients with miscarriage, 41 had D&C and 32 were given misoprostol. Baseline serum follicle stimulating hormone (FSH) levels and ovarian responses before and after treatment of miscarriage were comparable. No significant differences were observed between the D&C and the misoprostol groups in basal FSH levels, endometrial thickness and parameters of ovarian response in the subsequent IVF cycle. Conclusion: D&C and misoprostol are both effective treatments for IVF patients with miscarriage, without an adverse effect on subsequent IVF treatment outcome.

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KW - lag period

KW - miscarriage

KW - misoprostol

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The effect of medical versus surgical treatment of spontaneous miscarriage on subsequent in vitro fertilization cycles

Abstract

Keywords

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