The effect of latanoprost on accommodation in young patients with ocular hypertension

Purpose: To determine whether topical latanoprost 0.005% had an effect on accommodative capacity after 1 month of treatment in young patients with ocular hypertension. Patients and Methods: Fifteen patients (9 men and 6 women, aged 20-40 years) with ocular hypertension were instructed to instill the drug to their right eye for 1 month; the left eye received no medication and served as control. Near point of accommodation, refraction, and intraocular pressure (IOP) were determined after 1 month of treatment. Results: After 1 month of treatment with latanoprost, the mean IOP was reduced by 22.8% (5.8 mm Hg) in the treated eye and 1.86% (0.47 mm Hg) in the untreated control eye. No significant changes in refraction or near point of accommodation were observed in the treated or untreated eye. Conclusion: Short-term treatment with latanoprost 0.005% does not effect refraction or accommodation in young patients with ocular hypertension.