The effect of glucagon on plasma cyclic AMP levels in young and elderly subjects

J. Stessman, R. Eliakim, R. P. Ebstein

Research output: Contribution to journalArticlepeer-review

Abstract

Glucagon-induced rise in plasma cyclic AMP levels was used to study glucagon-sensitive adenylate cyclase activity in aged man. No significant difference was observed in plasma cyclic AMP rise after glucagon (0.0004 mg/kg) infusion between a group of 9 older (mean age 78 years) and 9 younger individuals (mean age 31 years). A similar rise in plasma glucose levels 10-15 min after glucagon administration was observed in both the younger and older individuals. These results are discussed in relation to previous findings of reduced beta-adrenergic-stimulated adenylate cyclase activity in aged man.

Original languageEnglish
Pages (from-to)71-74
Number of pages4
JournalAge
Volume7
Issue number3
DOIs
StatePublished - Jul 1984
Externally publishedYes

Fingerprint

Dive into the research topics of 'The effect of glucagon on plasma cyclic AMP levels in young and elderly subjects'. Together they form a unique fingerprint.

Cite this