TY - JOUR
T1 - The effect of gestational diabetes mellitus on human milk macronutrients content
AU - Shapira, Dana
AU - Mandel, Dror
AU - Mimouni, Francis B.
AU - Moran-Lev, Hadar
AU - Marom, Ronella
AU - Mangel, Laurence
AU - Lubetzky, Ronit
N1 - Publisher Copyright:
© 2019, Springer Nature America, Inc.
PY - 2019/6/1
Y1 - 2019/6/1
N2 - Objective: To test the null hypothesis that human milk (HM) macronutrients (fat, lactose, protein) and caloric content in women with gestational diabetes mellitus (GDM) is similar to that of women without GDM. Study design: Sixty-two lactating mothers (31 GDM, 31 no-GDM) were studied after confirmation by 100-g oral glucose tolerance test. Each mother contributed three manually expressed HM samples (within 72 h after labor (colostrum), after 7 days (transitional) and at 14 days (mature)). Analysis was done by infrared transmission spectroscopy. Results: Non-GDM and GDM groups did not differ by maternal age, pre-pregnancy weight, height, diet, pregnancy weight gain, gestational age, and infant birth weight. Macronutrients content in colostrum and transitional milk did not differ between groups. Fat and energy contents in mature HM were higher in non-GDM samples than in GDM samples (p = 0.07 and p < 0.02, respectively). Conclusion: Fat and energy content of mature HM obtained from mothers with GDM is lower compared to that of mature HM from mothers without GDM.
AB - Objective: To test the null hypothesis that human milk (HM) macronutrients (fat, lactose, protein) and caloric content in women with gestational diabetes mellitus (GDM) is similar to that of women without GDM. Study design: Sixty-two lactating mothers (31 GDM, 31 no-GDM) were studied after confirmation by 100-g oral glucose tolerance test. Each mother contributed three manually expressed HM samples (within 72 h after labor (colostrum), after 7 days (transitional) and at 14 days (mature)). Analysis was done by infrared transmission spectroscopy. Results: Non-GDM and GDM groups did not differ by maternal age, pre-pregnancy weight, height, diet, pregnancy weight gain, gestational age, and infant birth weight. Macronutrients content in colostrum and transitional milk did not differ between groups. Fat and energy contents in mature HM were higher in non-GDM samples than in GDM samples (p = 0.07 and p < 0.02, respectively). Conclusion: Fat and energy content of mature HM obtained from mothers with GDM is lower compared to that of mature HM from mothers without GDM.
UR - http://www.scopus.com/inward/record.url?scp=85063617563&partnerID=8YFLogxK
U2 - 10.1038/s41372-019-0362-5
DO - 10.1038/s41372-019-0362-5
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C2 - 30918340
AN - SCOPUS:85063617563
SN - 0743-8346
VL - 39
SP - 820
EP - 823
JO - Journal of Perinatology
JF - Journal of Perinatology
IS - 6
ER -
