The effect of codon usage on the success of horizontal gene transfer

Tamir Tuller*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

3 Scopus citations

Abstract

Horizontal gene transfer (HGT) is a central determinant of prokaryotic evolution. It was demonstrated that organisms with similar codon bias tend to be involved in more HGTs. Thus, dissimilarity in codon bias seems to be a central barrier to HGT. In this chapter, we will review the mechanisms by which codon bias contributes to the success of HGT. We also discuss the possibility that frequent HGT contributes to codon bias similarity within a microbial community, and the ramifications of these associations.

Original languageEnglish
Title of host publicationLateral Gene Transfer in Evolution
PublisherSpringer New York
Pages147-158
Number of pages12
Volume9781461477808
ISBN (Electronic)9781461477808
ISBN (Print)1461477794, 9781461477792
DOIs
StatePublished - 1 May 2013

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