TY - JOUR
T1 - The Effect of Changes in intraocular Pressure on Corneal Curvature after Radial Keratotomy in the Rabbit Eye
AU - Busin, Massimo
AU - Yau, Chi Wang
AU - Avni, Isaac
AU - McDonald, Marguerite B.
AU - Kaufman, Herbert E.
N1 - Funding Information:
Supported in part by PHS grants EY02580 and EY02377 from the National Eye Institute, National Institutes of Health, Bethesda, Maryland. Dr. Yau is presently affiliated with the Department of Ophthalmology, Mackay Memorial Hospital, Taipei, Taiwan.
PY - 1986
Y1 - 1986
N2 - Standard radial keratotomy was performed in both eyes of 18 rabbits. Intraocular pressure (IOP) was raised by injection of saline solution into the vitreous cavity at different times after surgery: 8 eyes at one, two, and six weeks and 12 eyes at four months. Keratometric readings at 10, 20, 40, 60, and 80 mmHg were recorded by three independent observers in a masked fasion. The same procedure was performed in eight eyes that had no surgery, as controls. Increments in IOP correlated with significant reductions in corneal power at all times after surgery and for all IOP values in the operated eyes. No changes were observed in the control eyes. The results indicate that variations in IOP, even within physiological limits, may cause changes in corneal curvature after radial keratotomy, and that patients with wide fluctuations in IOP could present a higher risk for postoperative fluctuation in visual acuity after this refractive procedure.
AB - Standard radial keratotomy was performed in both eyes of 18 rabbits. Intraocular pressure (IOP) was raised by injection of saline solution into the vitreous cavity at different times after surgery: 8 eyes at one, two, and six weeks and 12 eyes at four months. Keratometric readings at 10, 20, 40, 60, and 80 mmHg were recorded by three independent observers in a masked fasion. The same procedure was performed in eight eyes that had no surgery, as controls. Increments in IOP correlated with significant reductions in corneal power at all times after surgery and for all IOP values in the operated eyes. No changes were observed in the control eyes. The results indicate that variations in IOP, even within physiological limits, may cause changes in corneal curvature after radial keratotomy, and that patients with wide fluctuations in IOP could present a higher risk for postoperative fluctuation in visual acuity after this refractive procedure.
KW - albino rabbit
KW - corneal curvature
KW - intraocular pressure
KW - radial keratotomy
UR - http://www.scopus.com/inward/record.url?scp=0022481131&partnerID=8YFLogxK
U2 - 10.1016/S0161-6420(86)33739-4
DO - 10.1016/S0161-6420(86)33739-4
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AN - SCOPUS:0022481131
SN - 0161-6420
VL - 93
SP - 331
EP - 334
JO - Ophthalmology
JF - Ophthalmology
IS - 3
ER -