TY - JOUR
T1 - The effect of antilymphocyte serum on fetal rat intestine transplanted as free subcutaneous homografts
AU - Deutsch, Alexander A.
AU - Arensman, Robert M.
AU - Folkman, M. Judah
PY - 1974/2
Y1 - 1974/2
N2 - Fetal small bowel homografts of 4 cm were transplanted as free subcutaneous grafts in rats. One group received no immunosuppressive therapy and rejected the grafts by 8 days after initial vascularization. Two groups received rabbit anti-rat lymphocyte serum. They were rejected more slowly, and normal architecture was clearly seen at 26 days after transplantation, while some mucosa was recognizable 76 days after transplantation. The feasibility of this form of transplantation clinically is discussed and the suggestion made that intestinal transplants in humans should be initially undertaken only for accessory feeding.
AB - Fetal small bowel homografts of 4 cm were transplanted as free subcutaneous grafts in rats. One group received no immunosuppressive therapy and rejected the grafts by 8 days after initial vascularization. Two groups received rabbit anti-rat lymphocyte serum. They were rejected more slowly, and normal architecture was clearly seen at 26 days after transplantation, while some mucosa was recognizable 76 days after transplantation. The feasibility of this form of transplantation clinically is discussed and the suggestion made that intestinal transplants in humans should be initially undertaken only for accessory feeding.
UR - http://www.scopus.com/inward/record.url?scp=0015965850&partnerID=8YFLogxK
U2 - 10.1016/0022-3468(74)90006-2
DO - 10.1016/0022-3468(74)90006-2
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C2 - 4811251
AN - SCOPUS:0015965850
SN - 0022-3468
VL - 9
SP - 29
EP - 34
JO - Journal of Pediatric Surgery
JF - Journal of Pediatric Surgery
IS - 1
ER -