The Domino Effect in EGFR-ERK Signaling

Udi Binshtok, David Sprinzak*

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

4 Scopus citations

Abstract

A gradient of EGFR-ERK signaling has been classically implicated in various developmental processes. In this issue of Developmental Cell, Ogura et al. (2018) show that in the Drosophila tracheal placode, EGFR-ERK signaling propagates via a cell-by-cell relay mechanism rather than a gradient, and this sequential ERK activation controls proper placode invagination.

Original languageEnglish
Pages (from-to)128-130
Number of pages3
JournalDevelopmental Cell
Volume46
Issue number2
DOIs
StatePublished - 16 Jul 2018

Fingerprint

Dive into the research topics of 'The Domino Effect in EGFR-ERK Signaling'. Together they form a unique fingerprint.

Cite this