The current state of Clinical Mycology in Eastern and South-Eastern Europe

Cândida Driemeyer, Diego R. Falci, Martin Hoenigl, Oliver A. Cornely, Arunaloke Chakrabarti, Jean Pierre Gangneux, Esther Segal, Marika Jürna-Ellam, Tadeja Matos, Jacques F. Meis, John R. Perfect, Valentina Arsic Arsenijevic, Mihai Mares, Daniela Elena Serban, Alessandro C. Pasqualotto*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


The ability of medical centers in Eastern and South-Eastern Europe to diagnose and treat fungal infections remains unknown. In order to investigate that, here we conducted a cross-sectional online survey, released at both The International Society for Human & Animal Mycology (ISHAM) and European Confederation of Medical Mycology (ECMM) websites. A total of 31 institutions responded to the questionnaire. Most centers (87.1%, n = 27) had access to Aspergillus spp. ELISA galactomannan testing as well as to Cryptococcus spp. antigen testing (83.9%, n = 26). Serological tests were mostly available for Aspergillus species (80.6%, n = 25); and most institutions reported access to mold-active antifungal drugs (83.9%; n = 26), but 5-flucytosine was available to only 29% (n = 9) of the participant centers. In conclusion, this study represents the first attempt to document the strengths and limitations of the Eastern and South-Eastern European region for diagnosing and treating fungal diseases. Lay Summary: Our article is about the availability of diagnostic and treatments tools related to fungal infections in the countries of Eastern and South-Eastern region. Surveys like these are important to understand the gaps and point towards the fungal infections as a global health issue.

Original languageEnglish
Article numbermyac017
JournalMedical Mycology
Issue number4
StatePublished - 1 Apr 2022


  • Antifungal agents
  • Diagnosis
  • Fungal infection
  • Laboratory
  • Mycology


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