The Continuing Plague of Extended-spectrum β-lactamase–producing Enterobacteriaceae Infections

Amos Adler; David E. Katz; Dror Marchaim

doi:10.1016/j.idc.2016.02.003

The Continuing Plague of Extended-spectrum β-lactamase–producing Enterobacteriaceae Infections

Amos Adler
, David E. Katz
, Dror Marchaim^*

^*Corresponding author for this work

Tel Aviv Sourasky Medical Center
Hebrew University of Jerusalem
Assaf Harofeh Medical Center

Research output: Contribution to journal › Review article › peer-review

58 Scopus citations

Abstract

Antimicrobial resistance is a common iatrogenic complication of modern life and medical care. One of the most demonstrative examples is the exponential increase in the incidence of extended-spectrum β-lactamases (ESBLs) production among Enterobacteriaceae, which is the most common human pathogens outside of the hospital settings. Infections resulting from ESBL-producing bacteria are associated with devastating outcomes, now affecting even previously healthy individuals. This development poses an enormous burden and threat to public health. This paper aims to narrate the evolving epidemiology of ESBL infections, and highlight current challenges in terms of management and prevention of these common infections.

Original language	English
Pages (from-to)	347-375
Number of pages	29
Journal	Infectious Disease Clinics of North America
Volume	30
Issue number	2
DOIs	https://doi.org/10.1016/j.idc.2016.02.003
State	Published - 1 Jun 2016

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Escherichia coli
Gram-negative
Klebsiella pneumoniae
MDROs
Proteus mirabilis

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10.1016/j.idc.2016.02.003

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title = "The Continuing Plague of Extended-spectrum β-lactamase{\textendash}producing Enterobacteriaceae Infections",

abstract = "Antimicrobial resistance is a common iatrogenic complication of modern life and medical care. One of the most demonstrative examples is the exponential increase in the incidence of extended-spectrum β-lactamases (ESBLs) production among Enterobacteriaceae, which is the most common human pathogens outside of the hospital settings. Infections resulting from ESBL-producing bacteria are associated with devastating outcomes, now affecting even previously healthy individuals. This development poses an enormous burden and threat to public health. This paper aims to narrate the evolving epidemiology of ESBL infections, and highlight current challenges in terms of management and prevention of these common infections.",

keywords = "Escherichia coli, Gram-negative, Klebsiella pneumoniae, MDROs, Proteus mirabilis",

author = "Amos Adler and Katz, \{David E.\} and Dror Marchaim",

note = "Publisher Copyright: {\textcopyright} 2016 Elsevier Inc.",

year = "2016",

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language = "אנגלית",

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AU - Katz, David E.

AU - Marchaim, Dror

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Y1 - 2016/6/1

N2 - Antimicrobial resistance is a common iatrogenic complication of modern life and medical care. One of the most demonstrative examples is the exponential increase in the incidence of extended-spectrum β-lactamases (ESBLs) production among Enterobacteriaceae, which is the most common human pathogens outside of the hospital settings. Infections resulting from ESBL-producing bacteria are associated with devastating outcomes, now affecting even previously healthy individuals. This development poses an enormous burden and threat to public health. This paper aims to narrate the evolving epidemiology of ESBL infections, and highlight current challenges in terms of management and prevention of these common infections.

AB - Antimicrobial resistance is a common iatrogenic complication of modern life and medical care. One of the most demonstrative examples is the exponential increase in the incidence of extended-spectrum β-lactamases (ESBLs) production among Enterobacteriaceae, which is the most common human pathogens outside of the hospital settings. Infections resulting from ESBL-producing bacteria are associated with devastating outcomes, now affecting even previously healthy individuals. This development poses an enormous burden and threat to public health. This paper aims to narrate the evolving epidemiology of ESBL infections, and highlight current challenges in terms of management and prevention of these common infections.

KW - Escherichia coli

KW - Gram-negative

KW - Klebsiella pneumoniae

KW - MDROs

KW - Proteus mirabilis

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AN - SCOPUS:84991372921

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JO - Infectious Disease Clinics of North America

JF - Infectious Disease Clinics of North America

IS - 2

ER -

The Continuing Plague of Extended-spectrum β-lactamase–producing Enterobacteriaceae Infections

Abstract

UN SDGs

Keywords

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