TY - JOUR
T1 - The comparison of early follicular and midluteal administration of long-acting gonadotropin-releasing hormone agonist
AU - Ron-El, R.
AU - Herman, A.
AU - Golan, A.
AU - Van der Ven, H.
AU - Caspi, E.
AU - Diedrich, K.
PY - 1990
Y1 - 1990
N2 - Long-acting GnRH-a (D-Trp6 microcapsules, 3.2 mg) was intramuscularly injected, either in early follicular phase (group A) or midluteal phase (group B). Two hundred sixteen cycles were randomly allocated. Ovarian suppression was significantly more prompt in group B. Follicle cysts were diagnosed in 19% and 16% of groups A and B, respectively; their appearance and regression were significantly more rapid in group B cycles. More ampules of human menopausal gonadotropin were needed in group B. The number of oocytes retrieved was not significantly different between the groups. However, in group A more mature oocytes and more embryos with good morphology were achieved in the patients. Cancellation rate was 2.8% in groups A and B. Pregnancy rate and outcome were similar in both groups.
AB - Long-acting GnRH-a (D-Trp6 microcapsules, 3.2 mg) was intramuscularly injected, either in early follicular phase (group A) or midluteal phase (group B). Two hundred sixteen cycles were randomly allocated. Ovarian suppression was significantly more prompt in group B. Follicle cysts were diagnosed in 19% and 16% of groups A and B, respectively; their appearance and regression were significantly more rapid in group B cycles. More ampules of human menopausal gonadotropin were needed in group B. The number of oocytes retrieved was not significantly different between the groups. However, in group A more mature oocytes and more embryos with good morphology were achieved in the patients. Cancellation rate was 2.8% in groups A and B. Pregnancy rate and outcome were similar in both groups.
UR - http://www.scopus.com/inward/record.url?scp=0025079933&partnerID=8YFLogxK
U2 - 10.1016/S0015-0282(16)53695-4
DO - 10.1016/S0015-0282(16)53695-4
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AN - SCOPUS:0025079933
VL - 54
SP - 233
EP - 237
JO - Fertility and Sterility
JF - Fertility and Sterility
SN - 0015-0282
IS - 2
ER -