TY - JOUR
T1 - The clinical importance of factor XI deficiency in an Ashkenazi Jewish patient
AU - Heim, M.
AU - Ganel, A.
AU - Horoszowski, H.
AU - Farine, I.
PY - 1981/12
Y1 - 1981/12
N2 - Factor XI (PTA) deficiency, a coagulopathy, has been found to be relatively common in Ashkenazi Jews. Clinically it may manifest itself by varying forms of hemorrhage including postoperative bleeding. It is recommended that all Ashkenazi Jews have a partial thromboplastin time (PTT) coagulation test before surgery in order to rule out this coagulopathy, and if the PTT is abnormal a Factor XI assay should be done to confirm the diagnosis and ensure that proper therapy can be provided. A surgical case is presented with its ensuing complications resulting from lack of such information.
AB - Factor XI (PTA) deficiency, a coagulopathy, has been found to be relatively common in Ashkenazi Jews. Clinically it may manifest itself by varying forms of hemorrhage including postoperative bleeding. It is recommended that all Ashkenazi Jews have a partial thromboplastin time (PTT) coagulation test before surgery in order to rule out this coagulopathy, and if the PTT is abnormal a Factor XI assay should be done to confirm the diagnosis and ensure that proper therapy can be provided. A surgical case is presented with its ensuing complications resulting from lack of such information.
UR - http://www.scopus.com/inward/record.url?scp=0019857246&partnerID=8YFLogxK
U2 - 10.1097/00005373-198112000-00010
DO - 10.1097/00005373-198112000-00010
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C2 - 7321068
AN - SCOPUS:0019857246
SN - 2163-0755
VL - 21
SP - 1050
EP - 1051
JO - Journal of Trauma and Acute Care Surgery
JF - Journal of Trauma and Acute Care Surgery
IS - 12
ER -