The choice of therapy in medically intractable trigeminal neuralgia

Z. H. Rappaport*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Trigeminal neuralgia stands out as one of the few severe neuropathic pain states for which successful treatment options are available. Up to one-half of patients become refractory to medical therapy over time. At this point, the question of which intervention is appropriate becomes an important issue. A personal series of 150 patients treated between 1988 and 1995 is reviewed. Patients under 65 years and in good general health underwent surgery for microvascular decompression of the trigeminal root; in the remaining 120 patients glycerol was injected percutaneously into the trigeminal cistern. The results in these two patient groups is presented and the rationale of choosing an operative versus a percutaneous procedure is discussed in light of the outcome in this series and in the literature.

Original languageEnglish
Pages (from-to)1232-1234
Number of pages3
JournalIsrael Journal of Medical Sciences
Issue number12
StatePublished - Dec 1996
Externally publishedYes


  • Glycerol rhizolysis
  • Microvascular decompression
  • Trigeminal neuralgia


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