TY - JOUR
T1 - The associations of the Five Factor Model of personality with inflammatory biomarkers
T2 - A four-year prospective study
AU - Armon, Galit
AU - Melamed, Samuel
AU - Shirom, Arie
AU - Berliner, Shlomo
AU - Shapira, Itzhak
N1 - Funding Information:
This study was supported by Israel Science Foundation Grant 962/02-1 .
PY - 2013/4
Y1 - 2013/4
N2 - This study evaluated the associations of the Five Factor Model of personality with two inflammation biomarkers, C-reactive protein and fibrinogen, and the possible moderating effects of common health-related behaviors (physical activity and smoking) concurrently and over four years, while adjusting for socio-demographic and health status. Participants were individuals who underwent a health examination at two points of time, T1 (n=1709) and T2 (n=923), about four years apart. Regression analyses uncovered positive associations between Neuroticism and Extraversion with two inflammatory biomarkers at baseline (T1) and over time (T2) and increases in their levels over time. Additionally, a synergistic interaction of neuroticism and physical inactivity was associated with higher levels of inflammation biomarkers at both time periods. Openness was negatively associated with inflammation biomarkers at T1 and T2, but not with changes in their levels. No significant associations were found for Agreeableness and Conscientiousness. The results suggest that personality traits might be involved in the inflammatory process both concurrently and over time, and thus indicate a possible mechanism by which personality traits might influence health, especially cardiovascular disease risk.
AB - This study evaluated the associations of the Five Factor Model of personality with two inflammation biomarkers, C-reactive protein and fibrinogen, and the possible moderating effects of common health-related behaviors (physical activity and smoking) concurrently and over four years, while adjusting for socio-demographic and health status. Participants were individuals who underwent a health examination at two points of time, T1 (n=1709) and T2 (n=923), about four years apart. Regression analyses uncovered positive associations between Neuroticism and Extraversion with two inflammatory biomarkers at baseline (T1) and over time (T2) and increases in their levels over time. Additionally, a synergistic interaction of neuroticism and physical inactivity was associated with higher levels of inflammation biomarkers at both time periods. Openness was negatively associated with inflammation biomarkers at T1 and T2, but not with changes in their levels. No significant associations were found for Agreeableness and Conscientiousness. The results suggest that personality traits might be involved in the inflammatory process both concurrently and over time, and thus indicate a possible mechanism by which personality traits might influence health, especially cardiovascular disease risk.
KW - Big Five
KW - C-reactive protein (hsCRP)
KW - Cardiovascular disease
KW - Fibrinogen
KW - Five Factor Model
KW - Health behaviors
KW - Inflammation
KW - Longitudinal study
KW - Personality
UR - http://www.scopus.com/inward/record.url?scp=84873526380&partnerID=8YFLogxK
U2 - 10.1016/j.paid.2012.11.035
DO - 10.1016/j.paid.2012.11.035
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AN - SCOPUS:84873526380
VL - 54
SP - 750
EP - 755
JO - Personality and Individual Differences
JF - Personality and Individual Differences
SN - 0191-8869
IS - 6
ER -
