The Association of Helicobacter pylori, Eradication, and Early Complications of Laparoscopic Sleeve Gastrectomy

Adam Abu Abeid*, Subhi Abu Abeid, Eran Nizri, Joseph Kuriansky, Guy Lahat, Danit Dayan

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Purpose: Laparoscopic sleeve gastrectomy (SG) is a common and effective bariatric surgery, with low postoperative complication rates. It is important to define modifiable risk factors for complications. The possible association of Helicobacter pylori (HP) on SG outcomes is still being investigated. We aimed to examine HP prevalence in SG specimens, the association to early (30-day) complications, and impact of preoperative HP eradication on outcomes. Materials and Methods: This is a retrospective analysis of all consecutive patients who underwent SG between January 2012 and December 2020 in a single bariatric center. Data were retrieved from our prospectively maintained patient registry database. The 30-day outcomes were compared according to the HP status of the resected specimen: positive and negative, with or without preoperative HP eradication therapy. Results: There were 1985 patients; of them, 179 patients were HP positive and 1806 were HP negative in resected specimens. The overall early complication and major (Clavien-Dindo ≥ 3) complication rates were 8.6% and 3.2% (p = 0.48 and p = 0.21), respectively. A total of 111 patients were HP positive on preoperative endoscopic biopsy and received eradication therapy. All were HP negative on preoperative urea breath test, and 65.45% had HP negative resected specimens. HP eradication did not affect overall and major complications (p = 0.68 and p = 0.48, respectively). Conclusion: The presence of HP does not seem to affect the early outcomes of SG. HP eradication does not change the early postoperative course either. Therefore, the role of routine preoperative HP screening may be limited, and eradication can be completed following SG. Graphical Abstract: [Figure not available: see fulltext.]

Original languageEnglish
Pages (from-to)1617-1623
Number of pages7
JournalObesity Surgery
Issue number5
StatePublished - May 2022


  • Bariatric surgery
  • Early complications
  • Eradication
  • Helicobacter pylori
  • Morbid obesity
  • Sleeve gastrectomy


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