The alternative genome

Research output: Contribution to journalReview articlepeer-review


The recent developments in molecular biology which make it possible for a single gene to specify two or more distinct proteins are discussed. This is possible through a mechanism called alternative splicing, which edits the information stored in the genes of complex organisms in different ways. Different methods are developed by Randolph Wall, Tom Maniatis and a few other molecular biologists to develop a molecular machinery that performs the cutting of introns and pasting together of exons. The novel proteins created by the splicing methods can help to make humans.

Original languageEnglish
Pages (from-to)58-65
Number of pages8
JournalScientific American
Issue number4
StatePublished - Apr 2005


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