The 2018 assisi think tank meeting on breast cancer: International expert panel white paper

Meritxell Arenas, Ugur Selek, Orit Kaidar-Person, Elisabetta Perrucci, Angel Montero Luis, Liesbeth Boersma, Charlotte Coles, Birgitte Offersen, Icro Meattini, Yasemin Bölükbaşı, Maria Cristina Leonardi, Raphael Pfeffer, Bruno Cutuli, Cristiana Vidali, Pierfrancesco Franco, Vassilis Kouloulias, Valeria Masiello, Sofia Rivera, Céline Bourgier, Antonella CiabattoniValentina Lancellotta, Lurdes Trigo, Vincenzo Valentini, Philip Poortmans, Cynthia Aristei*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


We report on the second Assisi Think Tank Meeting (ATTM) on breast cancer which was held under the auspices of the European Society for RadioTherapy & Oncology (ESTRO). In discussing in-depth current evidence and practice it was designed to identify grey areas in diverse forms of the disease. It aimed at addressing uncertainties and proposing future trials to improve patient care. Before the meeting, three key topics were selected: 1) primary systemic therapy, mastectomy, breast reconstruction and post-mastectomy radiation therapy, 2) therapeutic options in ductal carcinoma in situ, and 3) therapy de-escalation in early stage breast cancer. Clinical practice in these areas was investigated by means of an online questionnaire. The time lapse period between the survey and the meeting was used to review the literature and on-going clinical trials. At the ATTM both were discussed in depth and research protocols were proposed.

Original languageEnglish
Article number102967
JournalCritical Reviews in Oncology/Hematology
StatePublished - Jul 2020
Externally publishedYes


FundersFunder number
National Institute for Health Research
UCLH Biomedical Research Centre


    • Breast cancer
    • Breast reconstruction
    • De-escalating therapy
    • Ductal carcinoma in situ
    • Hypofractionation
    • Neoadjuvant chemotherapy
    • Partial breast irradiation
    • Post-mastectomy radiation therapy
    • Radiation therapy


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