Technetium-99m-labeled red blood cell imaging

Dov Front*, Ora Israel, David Groshar, Jolie Weininger

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Red blood cells labeled with 99mTc constitute a suitable intravascular agent for imaging of vascular abnormalities. Hemangiomas are characterized by low perfusion and a high blood pool. This "perfusion blood-pool mismatch," not encountered in other lesions, may help in the specific diagnosis of this tumor. This is particularly so in cavernous hemangiomas of the liver where three-phase 99mTc-labeled red blood cell scintigraphy should precede liver biopsy. Red cell scintigraphy also is useful for estabishing the vascular nature of hemangiomas of the head and neck and the skin and for diagnosis of venous occlusion. Hear-damaged red blood cells provide a specific spleen imaging agent. This should be used when patients with suspected splenic pathology have equivocal colloid scintigraphy.

Original languageEnglish
Pages (from-to)226-250
Number of pages25
JournalSeminars in Nuclear Medicine
Issue number3
StatePublished - Jul 1984
Externally publishedYes


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