Tau, ADNP, and sex

Illana Gozes*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

With 50 years to the original discovery of Tau, I gave here my perspective, looking through the prism of activity-dependent neuroprotective protein (ADNP), and the influence of sex. My starting point was vasoactive intestinal peptide (VIP), a regulator of ADNP. I then moved to the original discovery of ADNP and its active neuroprotective site, NAP, drug candidate, davunetide. Tau–ADNP–NAP interactions were then explained with emphasis on sex and future translational medicine.

Original languageEnglish
Pages (from-to)16-23
Number of pages8
JournalCytoskeleton
Volume81
Issue number1
DOIs
StatePublished - Jan 2024

Funding

FundersFunder number
Anne and Alex Cohen
Elton Laboratory for Molecular Neuroendocrinology
Tel Aviv University

    Keywords

    • ADNP
    • NAP (davunetide)
    • Tau
    • sex

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