Systematic review of treatment effectiveness and outcome measures for enthesitis in psoriatic arthritis

Ana Maria Orbai, Joshua Weitz, Evan L. Siegel, Stefan Siebert, Laura J. Savage, Sibel Z. Aydin, Jolanda J. Luime, Ori Elkayam, Barbara Neerinckx, Slavo Urbancek, Kurt De Vlam, Christopher T. Ritchlin

Research output: Contribution to journalReview articlepeer-review

Abstract

Enthesitis is a characteristic feature of psoriatic arthritis (PsA) and is important in disease pathogenesis and classification. Use of clinical outcome measures for enthesitis is heterogeneous, and only 1 measure has been specifically developed and validated in PsA. Ultrasound and magnetic resonance imaging assessments of enthesitis may have advantages over clinical examination but are insufficiently studied. As part of an update of treatment recommendations by the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA), we performed a systematic literature review and identified randomized controlled trials with enthesitis outcomes in PsA. For each treatment agent we calculated treatment effect sizes (where applicable) and graded the level of evidence.

Original languageEnglish
Pages (from-to)2290-2294
Number of pages5
JournalJournal of Rheumatology
Volume41
Issue number11
DOIs
StatePublished - 1 Nov 2014
Externally publishedYes

Keywords

  • Enthesitis
  • Enthesopathy psoriatic arthritis
  • Outcome measures
  • Treatment

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