Synthesis of pyrido[2,3,4-kl]acridines a building block for the synthesis of pyridoacridine alkaloids

Gari Gellerman; Amira Rudi; Yoel Kashman

doi:10.1016/S0040-4039(00)61150-4

Synthesis of pyrido[2,3,4-kl]acridines a building block for the synthesis of pyridoacridine alkaloids

Gari Gellerman^*, Amira Rudi, Yoel Kashman

^*Corresponding author for this work

School of Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

Two new syntheses have been developed for the preparation of substituted pyrido[2,3,4-kl]acridines. The first synthesis involves a Skraup reaction and a nitrene insertion whereas the second includes a new pyridine ring synthesis starting from a 1-amino group on acridine and taking advantage of the active 9-position of the latter heterocycle.

Original language	English
Pages (from-to)	5577-5580
Number of pages	4
Journal	Tetrahedron Letters
Volume	33
Issue number	38
DOIs	https://doi.org/10.1016/S0040-4039(00)61150-4
State	Published - 15 Sep 1992

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title = "Synthesis of pyrido[2,3,4-kl]acridines a building block for the synthesis of pyridoacridine alkaloids",

abstract = "Two new syntheses have been developed for the preparation of substituted pyrido[2,3,4-kl]acridines. The first synthesis involves a Skraup reaction and a nitrene insertion whereas the second includes a new pyridine ring synthesis starting from a 1-amino group on acridine and taking advantage of the active 9-position of the latter heterocycle.",

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AU - Rudi, Amira

AU - Kashman, Yoel

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Y1 - 1992/9/15

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AB - Two new syntheses have been developed for the preparation of substituted pyrido[2,3,4-kl]acridines. The first synthesis involves a Skraup reaction and a nitrene insertion whereas the second includes a new pyridine ring synthesis starting from a 1-amino group on acridine and taking advantage of the active 9-position of the latter heterocycle.

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Synthesis of pyrido[2,3,4-kl]acridines a building block for the synthesis of pyridoacridine alkaloids

Abstract

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