Synthesis of hydroxyapatite from Lates calcarifer fish bone for biomedical applications

Anindya Pal; Sudeep Paul; Amit Roy Choudhury; Vamsi Krishna Balla; Mitun Das; Arijit Sinha

doi:10.1016/j.matlet.2017.05.103

Synthesis of hydroxyapatite from Lates calcarifer fish bone for biomedical applications

Anindya Pal, Sudeep Paul, Amit Roy Choudhury, Vamsi Krishna Balla, Mitun Das^*, Arijit Sinha

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

The present study aims at the synthesis of hydroxyapatite (HAp) from fish bone by simple heat treatment in the temperature ranging from 200 to 1200 °C. The synthesized powders were characterized using X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR) to identify the phases and functional groups. The major phase was hydroxyapatite in all the powders and small amount of tricalcium phosphate observed in the calcined powders above 800 °C. The FTIR results showed phosphate, hydroxyl peaks in the samples treated at high temperatures (>800 °C) and other groups corresponding to carbonates and collagen were not present. The high resolution transmission electron microscopy (HRTEM) of the powder calcined at 1200 °C demonstrated irregular morphology and composition detected using energy dispersive spectroscopy. The in vitro biocompatibility study of fish (Lates calcarifer) bone derived HAp powder, sintered at 1200 °C, showed that these powders are non-cytotoxic.

Original language	English
Pages (from-to)	89-92
Number of pages	4
Journal	Materials Letters
Volume	203
DOIs	https://doi.org/10.1016/j.matlet.2017.05.103
State	Published - 15 Sep 2017
Externally published	Yes

Keywords

Bioceramics
Biocompatibility
Cytotoxicity
Fish bones
Hydroxyapatite
Sintering

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10.1016/j.matlet.2017.05.103

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title = "Synthesis of hydroxyapatite from Lates calcarifer fish bone for biomedical applications",

abstract = "The present study aims at the synthesis of hydroxyapatite (HAp) from fish bone by simple heat treatment in the temperature ranging from 200 to 1200 °C. The synthesized powders were characterized using X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR) to identify the phases and functional groups. The major phase was hydroxyapatite in all the powders and small amount of tricalcium phosphate observed in the calcined powders above 800 °C. The FTIR results showed phosphate, hydroxyl peaks in the samples treated at high temperatures (>800 °C) and other groups corresponding to carbonates and collagen were not present. The high resolution transmission electron microscopy (HRTEM) of the powder calcined at 1200 °C demonstrated irregular morphology and composition detected using energy dispersive spectroscopy. The in vitro biocompatibility study of fish (Lates calcarifer) bone derived HAp powder, sintered at 1200 °C, showed that these powders are non-cytotoxic.",

keywords = "Bioceramics, Biocompatibility, Cytotoxicity, Fish bones, Hydroxyapatite, Sintering",

author = "Anindya Pal and Sudeep Paul and Choudhury, {Amit Roy} and Balla, {Vamsi Krishna} and Mitun Das and Arijit Sinha",

note = "Publisher Copyright: {\textcopyright} 2017 Elsevier B.V.",

year = "2017",

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day = "15",

doi = "10.1016/j.matlet.2017.05.103",

language = "אנגלית",

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AU - Pal, Anindya

AU - Paul, Sudeep

AU - Choudhury, Amit Roy

AU - Balla, Vamsi Krishna

AU - Das, Mitun

AU - Sinha, Arijit

PY - 2017/9/15

Y1 - 2017/9/15

N2 - The present study aims at the synthesis of hydroxyapatite (HAp) from fish bone by simple heat treatment in the temperature ranging from 200 to 1200 °C. The synthesized powders were characterized using X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR) to identify the phases and functional groups. The major phase was hydroxyapatite in all the powders and small amount of tricalcium phosphate observed in the calcined powders above 800 °C. The FTIR results showed phosphate, hydroxyl peaks in the samples treated at high temperatures (>800 °C) and other groups corresponding to carbonates and collagen were not present. The high resolution transmission electron microscopy (HRTEM) of the powder calcined at 1200 °C demonstrated irregular morphology and composition detected using energy dispersive spectroscopy. The in vitro biocompatibility study of fish (Lates calcarifer) bone derived HAp powder, sintered at 1200 °C, showed that these powders are non-cytotoxic.

AB - The present study aims at the synthesis of hydroxyapatite (HAp) from fish bone by simple heat treatment in the temperature ranging from 200 to 1200 °C. The synthesized powders were characterized using X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR) to identify the phases and functional groups. The major phase was hydroxyapatite in all the powders and small amount of tricalcium phosphate observed in the calcined powders above 800 °C. The FTIR results showed phosphate, hydroxyl peaks in the samples treated at high temperatures (>800 °C) and other groups corresponding to carbonates and collagen were not present. The high resolution transmission electron microscopy (HRTEM) of the powder calcined at 1200 °C demonstrated irregular morphology and composition detected using energy dispersive spectroscopy. The in vitro biocompatibility study of fish (Lates calcarifer) bone derived HAp powder, sintered at 1200 °C, showed that these powders are non-cytotoxic.

KW - Bioceramics

KW - Biocompatibility

KW - Cytotoxicity

KW - Fish bones

KW - Hydroxyapatite

KW - Sintering

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VL - 203

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JO - Materials Letters

JF - Materials Letters

ER -

Synthesis of hydroxyapatite from Lates calcarifer fish bone for biomedical applications

Abstract

Keywords

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