@article{afa84cdb0ced484ab9603c24aec03739,
title = "Synthesis and evaluation of membrane permeabilizing properties of cationic amphiphiles derived from the disaccharide trehalose",
abstract = "Cationic amphiphiles derived from trehalose have been synthesized; trehalose analogues substituted with n-pentyl or n-hexyl ethers exhibited membrane disrupting activities against clinically important Gram positive and Gram negative bacteria and fungi. Our results demonstrate that trehalose is a useful disaccharide scaffold for the development of broad-spectrum antimicrobial and antifungal agents.",
author = "P. Shaul and Benhamou, {R. I.} and Herzog, {I. M.} and {Louzoun Zada}, S. and Y. Ebenstein and M. Fridman",
note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry 2016.",
year = "2016",
doi = "10.1039/c6ob00031b",
language = "אנגלית",
volume = "14",
pages = "3012--3015",
journal = "Organic and Biomolecular Chemistry",
issn = "1477-0520",
publisher = "Royal Society of Chemistry",
number = "11",
}