Synchronous airway lesions in laryngomalacia

Eilon Krashin, Josef Ben-Ari, Chaim Springer, Ari DeRowe, Avraham Avital, Yakov Sivan*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

35 Scopus citations


Objective: Laryngomalacia is the most common cause of congenital stridor. Laryngomalacia may be associated with other structural and functional airway lesions. While previous studies suggested a 10-45% rate of synchronous airway lesions (SALs), the exact rate and it's clinical significance is unknown. The purpose of this study was to determine the prevalence of SALs below the glottic level in congenital laryngomalacia, and to investigate possible relations with other clinical findings. Methods: A cohort of 228 infants with congenital stridor who underwent fiberoptic flexible bronchoscopy (FFB) was analyzed. Data was collected from the hospital records. All procedures were reevaluated from the video recordings. Results: SALs below the vocal cords were observed in 7.5% of the case (17/228). The most common SAL was tracheal bronchus followed by tracheomalacia and stenosis of the left main bronchus. No correlation was found between the presence of a SAL below the vocal cords and any other medical condition except for neurodevelopmental disorders. Except for one patient, all cases with SAL did not have any clinical symptoms or signs that would have suggested an accompanying airway lesion. Conclusions: The rate of SALs in infants with congenital stridor due to laryngomalacia is low and most of the additional lesions are benign. The yield of discovering clinically significant SALs below the glottic level is low and the routine search for a synchronous lesion below the vocal cords should be questioned. Except for underlying neurodevelopmental problems, no clear risk factors for the existence of SALs were identified.

Original languageEnglish
Pages (from-to)501-507
Number of pages7
JournalInternational Journal of Pediatric Otorhinolaryngology
Issue number4
StatePublished - Apr 2008
Externally publishedYes


  • Bronchoscopy
  • Congenital stridor
  • Infant
  • Laryngomalacia
  • Laryngoscopy


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