Survival and prognostic factors in chronic lymphocytic leukemia

Amos Pines*, Isaac Ben‐Bassat, Michaela Modan, Tzvia Blumstein, Bracha Ramot

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


The survival of 137 consecutive chronic lymphocytic leukemia patients, diagnosed between 1960 and 1982 and followed up at the Hematology Clinic of the Chaim Sheba Center, was correlated with demographic, clinical and laboratory data. The median survival time of the whole group was 104 months. Older age, hepatomegaly, anemia, thrombocytopenia and increased percent of lymphocytes in the peripheral blood at diagnosis were all associated with shorter survival. On the other hand, splenomegaly or lymph node enlargement did not influence survival. When divided according to both Rai's and the International Workshop staging systems, the survival of our patients seemed to be better than that reported in most previously published series of similar patients. We assume that this is related to a conservative approach to the treatment of chronic lymphocytic leukemia patients in this center.

Original languageEnglish
Pages (from-to)123-130
Number of pages8
JournalEuropean Journal of Haematology
Issue number2
StatePublished - Feb 1987


  • chronic lymphocytic leukemia
  • prognosis
  • survival


Dive into the research topics of 'Survival and prognostic factors in chronic lymphocytic leukemia'. Together they form a unique fingerprint.

Cite this