Background The injection of large volumes of silicone oil for lip augmentation can lead to the formation of abnormally prominent or projected lips. Conservative treatment measures are largely ineffective. This observational study describes the application of a surgical technique developed at our center for the correction of silicone oil-induced lip deformities. Participants and Methods Fifty-nine patients presented at a tertiary medical center over a 6-year period with complaints of lip deformities caused by injections of silicone oil for lip augmentation 2 to 4 years previously. All had proven refractory to conservative treatment. The patients underwent individually tailored surgery consisting of a series of wedge-like incisions and Z-plasties to reproduce a normal lip line. Results Patients returned to their normal daily routine after 3 to 7 days. Only two patients (3.4%) required revision surgery after 6 months to correct lip asymmetry. Ninety percent of the patients expressed satisfaction with the aesthetic and functional outcome after 3 months. Conclusion Our innovative, individually tailored surgical technique for the correction of lip deformities due to silicone oil injection for lip augmentation is simple and safe to perform and yields a satisfactory outcome in most cases.