Surgical management of metastatic bone disease

Jacob Bickels, Shlomo Dadia, Zvi Lidar

Research output: Contribution to journalReview articlepeer-review


▶ Metastatic bone disease is a major contributor to the deterioration of the quality of life of patients with cancer; it causes pain, impending and actual pathological fractures, and loss of function and may also be associated with considerable metabolic alterations. ▶ Operative treatment may be required for an impending or existing fracture and intractable pain. The goals of surgery are to provide local tumor control and allow immediate weight-bearing and function. Radiation therapy is often indicated postoperatively. ▶ Detailed preoperative evaluation is required to assess the local extent of bone destruction and soft-tissue involvement, involvement of other skeletal sites, and the overall medical and oncological status.

Original languageEnglish
Pages (from-to)1503-1516
Number of pages14
JournalJournal of Bone and Joint Surgery - Series A
Issue number6
StatePublished - 1 Jun 2009
Externally publishedYes


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