Suppressor mononuclear cells in giant lymph node hyperplasia and thymoma

B. Shohat*, I. Cohen, R. Fogel, R. Zaizov

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The existence of suppressor mononuclear cells were demonstrated in two lymphoproliferative disorders: giant lymph node hyperplasia and thymona. The three patients tested also showed cell‐mediated immunodeficiency as expressed in the low number of T cells, negative graft versus host reactions and negative skin tests; the one patient tested with phytohemagglutinin (PHA) and concavalin A (Con A) showed a low response. Suppressor activity was tested with a new experimental model, the local xenogeneic graft versus host reaction. It is proposed that this model be used for testing suppressor activities in other human disorders as well.

Original languageEnglish
Pages (from-to)923-926
Number of pages4
JournalCancer
Volume48
Issue number4
DOIs
StatePublished - 15 Aug 1981

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