TY - JOUR
T1 - Suppression of Hypoglycemia by DL-Propranolol in Malignant Insulinoma
AU - Blum, I.
AU - Aderka, D.
AU - Doron, M.
AU - Laron, Z.
PY - 1978/8/31
Y1 - 1978/8/31
N2 - To the Editor: Reports have described the beneficial role of DL-propranolol in relieving hypoglycemic attacks in patients suffering from insulinoma.1 2 3 With the aim of determining whether the glucose-elevating effect of the DL-propranolol was due to the membrane-stabilizing or to beta-adrenergic blocking activity,4 the effect of this drug was compared with that of D-propranolol in a patient with malignant insulinoma (the details of the clinical course of this patient have been described elsewhere3). The patient, who had previously been severely hypoglycemic and suffering from convulsive fits, was symptom free and normoglycemic on DL-propranolol (640 mg per day) for 45 days. No extract is available for articles shorter than 400 words.
AB - To the Editor: Reports have described the beneficial role of DL-propranolol in relieving hypoglycemic attacks in patients suffering from insulinoma.1 2 3 With the aim of determining whether the glucose-elevating effect of the DL-propranolol was due to the membrane-stabilizing or to beta-adrenergic blocking activity,4 the effect of this drug was compared with that of D-propranolol in a patient with malignant insulinoma (the details of the clinical course of this patient have been described elsewhere3). The patient, who had previously been severely hypoglycemic and suffering from convulsive fits, was symptom free and normoglycemic on DL-propranolol (640 mg per day) for 45 days. No extract is available for articles shorter than 400 words.
UR - http://www.scopus.com/inward/record.url?scp=0018165854&partnerID=8YFLogxK
U2 - 10.1056/NEJM197808312990918
DO - 10.1056/NEJM197808312990918
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AN - SCOPUS:0018165854
SN - 0028-4793
VL - 299
SP - 487
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 9
ER -