Supportive care during pediatric hematopoietic stem cell transplantation: beyond infectious diseases. A report from workshops on supportive care of the Pediatric Diseases Working Party (PDWP) of the European Society for Blood and Marrow Transplantation (EBMT)

Tiago Nava, Marc Ansari, Jean Hugues Dalle, Christina Diaz de Heredia, Tayfun Güngör, Eugenia Trigoso, Ulrike Falkenberg, Alice Bertaina, Brenda Gibson, Andrea Jarisch, Adriana Balduzzi, Halvard Boenig, Gergely Krivan, Kim Vettenranta, Toni Matic, Jochen Buechner, Krzysztof Kalwak, Anita Lawitschka, Akif Yesilipek, Giovanna LucchiniChristina Peters, Dominik Turkiewicz, Riitta Niinimäki, Tamara Diesch, Thomas Lehrnbecher, Petr Sedlacek, Daphna Hutt, Arnaud Dalissier, Jacek Wachowiak, Isaac Yaniv, Jerry Stein, Koray Yalçin, Luisa Sisinni, Marco Deiana, Marianne Ifversen, Michaela Kuhlen, Roland Meisel, Shahrzad Bakhtiar, Simone Cesaro, Andre Willasch, Selim Corbacioglu, Peter Bader*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Hematopoietic stem cell transplantation (HSCT) is currently the standard of care for many malignant and nonmalignant blood diseases. As several treatment-emerging acute toxicities are expected, optimal supportive measurements critically affect HSCT outcomes. The paucity of good clinical studies in supportive practices gives rise to the establishment of heterogeneous guidelines across the different centers, which hampers direct clinical comparison in multicentric studies. Aiming to harmonize the supportive care provided during the pediatric HSCT in Europe, the Pediatric Diseases Working Party (PDWP) of the European Society for Blood and Marrow Transplantation (EBMT) promoted dedicated workshops during the years 2017 and 2018. The present paper describes the resulting consensus on the management of sinusoidal obstructive syndrome, mucositis, enteral and parenteral nutrition, iron overload, and emesis during HSCT.

Original languageEnglish
Pages (from-to)1126-1136
Number of pages11
JournalBone Marrow Transplantation
Volume55
Issue number6
DOIs
StatePublished - 1 Jun 2020
Externally publishedYes

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