Abstract
Single-scan MRI underlies a wide variety of clinical and research activities, including functional and diffusion studies. Most common among these "ultrafast" MRI approaches is echo-planar imaging. Notwithstanding its proven success, echo-planar imaging still faces a number of limitations, particularly as a result of susceptibility heterogeneities and of chemical shift effects that can become acute at high fields. The present study explores a new approach for acquiring multidimensional MR images in a single scan, which possesses a higher built-in immunity to this kind of heterogeneity while retaining echo-planar imaging's temporal and spatial performances. This new protocol combines a novel approach to multidimensional spectroscopy, based on the spatial encoding of the spin interactions, with image reconstruction algorithms based on super-resolution principles. Single-scan two-dimensional MRI examples of the performance improvements provided by the resulting imaging protocol are illustrated using phantom-based and in vivo experiments.
Original language | English |
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Pages (from-to) | 1594-1600 |
Number of pages | 7 |
Journal | Magnetic Resonance in Medicine |
Volume | 63 |
Issue number | 6 |
DOIs | |
State | Published - Jun 2010 |
Externally published | Yes |
Keywords
- EPI
- Single-scan imaging
- Spatial encoded imaging
- Super-resolution
- Susceptibility compensation
- Ultrafast MRI