Sulpiride adjunction to clozapine in treatment-resistant schizophrenic patients: A preliminary case series study

R. Shiloh; Z. Zemishlany; D. Aizenberg; A. Weizman

doi:10.1016/S0924-9338(97)80205-2

Sulpiride adjunction to clozapine in treatment-resistant schizophrenic patients: A preliminary case series study

R. Shiloh, Z. Zemishlany, D. Aizenberg, A. Weizman^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

Six chronic neuroleptic-resistant schizophrenic patients, partial responders to clozapine, were co-administered 600 mg/day of sulpiride (a selective D₂ dopaminergic antagonist) as an augmentation to clozapine (a relatively weak D₂ blocker), for 10 weeks, open-labeled. A remarkable reduction in positive and negative symptoms was observed in four of the six patients.

Original language	English
Pages (from-to)	152-155
Number of pages	4
Journal	European Psychiatry
Volume	12
Issue number	3
DOIs	https://doi.org/10.1016/S0924-9338(97)80205-2
State	Published - 1997
Externally published	Yes

Funding

Funders	Funder number
Emouna Foundation

Keywords

clozapine
dopamine
prolactin
schizophrenia
sulpiride

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10.1016/S0924-9338(97)80205-2

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title = "Sulpiride adjunction to clozapine in treatment-resistant schizophrenic patients: A preliminary case series study",

abstract = "Six chronic neuroleptic-resistant schizophrenic patients, partial responders to clozapine, were co-administered 600 mg/day of sulpiride (a selective D2 dopaminergic antagonist) as an augmentation to clozapine (a relatively weak D2 blocker), for 10 weeks, open-labeled. A remarkable reduction in positive and negative symptoms was observed in four of the six patients.",

keywords = "clozapine, dopamine, prolactin, schizophrenia, sulpiride",

author = "R. Shiloh and Z. Zemishlany and D. Aizenberg and A. Weizman",

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AU - Aizenberg, D.

AU - Weizman, A.

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PY - 1997

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KW - dopamine

KW - prolactin

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Sulpiride adjunction to clozapine in treatment-resistant schizophrenic patients: A preliminary case series study

Abstract

Funding

Keywords

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