Sulfasalazine Pneumonitis

Mordechai Averbuch, Zamir Halpern, Aharon Hallak, Marcel Topilsky, Yoram Levo

Research output: Contribution to journalArticlepeer-review


A patient with ulcerative colitis developed skin allergy to sulfasalazine, manifested by rash urticaria and generalized angioedema. The patient underwent desensitization with the drug. After desensitization, the drug was reinstituted without any adverse skin reaction. However, 2 months later the patient developed a severe pneumonitis that resolved completely on discontinuation of sulfasalazine and administration of steroids. The relationship between the various adverse reactions to the drug is discussed and the entity “sulfasalazine pneumonitis” is reviewed.

Original languageEnglish
Pages (from-to)343-345
Number of pages3
JournalAmerican Journal of Gastroenterology
Issue number5
StatePublished - May 1985


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