TY - JOUR
T1 - Sulfasalazine Pneumonitis
AU - Averbuch, Mordechai
AU - Halpern, Zamir
AU - Hallak, Aharon
AU - Topilsky, Marcel
AU - Levo, Yoram
PY - 1985/5
Y1 - 1985/5
N2 - A patient with ulcerative colitis developed skin allergy to sulfasalazine, manifested by rash urticaria and generalized angioedema. The patient underwent desensitization with the drug. After desensitization, the drug was reinstituted without any adverse skin reaction. However, 2 months later the patient developed a severe pneumonitis that resolved completely on discontinuation of sulfasalazine and administration of steroids. The relationship between the various adverse reactions to the drug is discussed and the entity “sulfasalazine pneumonitis” is reviewed.
AB - A patient with ulcerative colitis developed skin allergy to sulfasalazine, manifested by rash urticaria and generalized angioedema. The patient underwent desensitization with the drug. After desensitization, the drug was reinstituted without any adverse skin reaction. However, 2 months later the patient developed a severe pneumonitis that resolved completely on discontinuation of sulfasalazine and administration of steroids. The relationship between the various adverse reactions to the drug is discussed and the entity “sulfasalazine pneumonitis” is reviewed.
UR - http://www.scopus.com/inward/record.url?scp=0021837749&partnerID=8YFLogxK
U2 - 10.1111/j.1572-0241.1985.tb02114.x
DO - 10.1111/j.1572-0241.1985.tb02114.x
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AN - SCOPUS:0021837749
SN - 0002-9270
VL - 80
SP - 343
EP - 345
JO - American Journal of Gastroenterology
JF - American Journal of Gastroenterology
IS - 5
ER -