BACKGROUND: Data concerning medical treatment of interstitial ectopic pregnancies are scarce. These pregnancies are characterized by late and serious clinical manifestations. We report a case of advanced interstitial pregnancy treated successfully by combining methotrexate (MTX) and hysteroscopy. CASE: A routine ultrasonic evaluation of a 10-week pregnancy revealed a right interstitial gestational sac 58 mm in diameter and containing an embryo with a crown-rump length of 29 mm and embryonic heartbeats. Serum β-human chorionic gonadatropin (hCG) level was 97,950 mIU/mL. The patient was treated with a systemic MTX/leucovorin regimen. At the end of the one-week course, no embryonic cardiac activity was detected, and a decrease in β-hCG levels commenced. Persistent trophoblastic tissue, manifested by a low (26 mIU/mL) β-hCG level in plateau, was successfully removed by way of hysteroscopy. CONCLUSION: Early detection of interstitial pregnancy amy facilitate conservative medical treatment.
|Number of pages||4|
|Journal||The Journal of reproductive medicine|
|State||Published - Aug 1998|
- Pregnancy, ectopic
- Pregnancy, interstitial