Successful therapeutic splenectomy in an HIV patient with relapsing visceral leishmaniasis

D. Alon*, M. Chowers

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Summary: A 43-year-old HIV-positive Ethiopian immigrant presented with persistent diarrhoea, hepatosplenomegaly and pancytopaenia. Visceral leishmaniasis was diagnosed by multiple gastrointestinal tract biopsies. Blood polymerase chain reaction (PCR) was positive for Leishmania donovani. Despite highly active antiretroviral therapy (HAART) and multiple courses of antileishmanial treatments, including liposomal amphotericin and sodium stibogluconate, the patient had multiple relapses. CD4 counts remained at 40-60 cells/μL although viral loads were undetectable. Splenectomy resulted in resolution of the patient's pancytopaenia and in rising CD4 levels, which enabled a long-lasting remission.

Original languageEnglish
Pages (from-to)289-290
Number of pages2
JournalInternational Journal of STD and AIDS
Issue number4
StatePublished - Apr 2012
Externally publishedYes


  • HIV
  • Leishmania donovani
  • Splenectomy
  • Visceral leishmaniasis


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