Objective: Methylphenidate is a cornerstone of attention-deficit/ hyperactivity disorder (ADHD) treatment. Cutaneous adverse reactions resulting from methylphenidate may prohibit its usage. We sought a way to continue this therapy in a patient who developed a rash twice following methylphenidate administration. Methods: In a desensitization protocol, methylphenidate was given in increasing doses, 30 minutes apart, over 10 days, until the therapeutic dose was reached and was continued regularly thereafter. Results: No adverse reactions developed during the desensitization period or during the 6-month follow-up. Conclusions: In nonlife threatening cutaneous adverse reactions to methylphenidate, a desensitization protocol may enable the continued, safe administration of this drug.
|Number of pages||3|
|Journal||Journal of Child and Adolescent Psychopharmacology|
|State||Published - Aug 2005|