TY - JOUR
T1 - Subject-specific p-FE analysis of the proximal femur utilizing micromechanics-based material properties
AU - Yosibash, Zohar
AU - Trabelsi, Nir
AU - Hellmich, Christian
PY - 2008
Y1 - 2008
N2 - Novel subject-specific high-order finite element models of the human femur based on computer tomographic (CT) data are discussed with material properties determined by two different methods, empirically based and micromechanics based, both being determined from CT scans. The finite element (FE) results are validated through strain measurements on a femur harvested from a 54-year-old female. To the best of our knowledge, this work is the first to consider an inhomogeneous Poisson ratio and the first to compare results obtained by micromechanics-based material properties to experimental observations on a whole organ. We demonstrate that the FE models with the micromechanics-based material properties yield results which closely match the experimental observations and are in accordance with the empirically based FE models. Because the p-FE micromechanics-based results match independent experimental observations and may provide access to patient-specific distribution of the full elasticity tensor components, it is recommended to use a micromechanics-based method for subject-specific structural mechanics analyses of a human femur.
AB - Novel subject-specific high-order finite element models of the human femur based on computer tomographic (CT) data are discussed with material properties determined by two different methods, empirically based and micromechanics based, both being determined from CT scans. The finite element (FE) results are validated through strain measurements on a femur harvested from a 54-year-old female. To the best of our knowledge, this work is the first to consider an inhomogeneous Poisson ratio and the first to compare results obtained by micromechanics-based material properties to experimental observations on a whole organ. We demonstrate that the FE models with the micromechanics-based material properties yield results which closely match the experimental observations and are in accordance with the empirically based FE models. Because the p-FE micromechanics-based results match independent experimental observations and may provide access to patient-specific distribution of the full elasticity tensor components, it is recommended to use a micromechanics-based method for subject-specific structural mechanics analyses of a human femur.
KW - Bone biomechanics
KW - Computed tomography (CT)
KW - Continuum micromechanics
KW - Finite element analysis
KW - P-FEM
KW - Proximal femur
KW - X-ray attenuation
UR - http://www.scopus.com/inward/record.url?scp=62749155714&partnerID=8YFLogxK
U2 - 10.1615/IntJMultCompEng.v6.i5.70
DO - 10.1615/IntJMultCompEng.v6.i5.70
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AN - SCOPUS:62749155714
SN - 1543-1649
VL - 6
SP - 483
EP - 498
JO - International Journal for Multiscale Computational Engineering
JF - International Journal for Multiscale Computational Engineering
IS - 5
ER -