Studies on mutations disruptive to nuclear migration in Schizophyllum commune

The pattern of complementation between mutations disruptive to nuclear migration was studied in an attempt to obtain an estimate of the number of genes implicated in the morphogenetic process of nuclear migration. The results indicate that a direct estimate cannot be obtained directly from the pattern of interactions due to the complexity of the pattern. It is shown that nonallelic genes can lead to an interaction normally obtained between mutations in the same gene. The pattern of interactions between the mutants and with the wild type suggest that the mutations disruptive to nuclear migration involve the biochemical modification of septal components.