Structure-dynamic coupling through Ca²⁺-binding regulatory domains of mammalian NCX isoform/splice variants

Keyphrases

• Structure Dynamics 100%
• Ca2+ Dependence 100%
• Splice Variant 100%
• Ca2+ Binding 100%
• Regulatory Domain 100%
• Dynamic Coupling 100%
• Ca2+ 83%
• Cassette Exons 50%
• NCX1 50%
• NCX3 50%
• Mutually Exclusive Exons 50%
• Na + 33%
• Exon 33%
• NCX2 33%
• Alleviation 16%
• Salt Bridge 16%
• Common Mechanisms 16%
• Regulatory Pathways 16%
• Ion Exchanger 16%
• Slow Dissociation 16%
• Dynamic Features 16%
• Interdomain Linker 16%
• Conformational States 16%
• Control Dynamics 16%
• Activation Control 16%
• Global Conformational Changes 16%
• Population Shift 16%
• Off-rate 16%
• Rigidification 16%
• Backbone Dynamics 16%
• Regulatory Requirements 16%
• Fine Adjustment 16%
• Exon Assembly 16%
• Feature Match 16%
• Interdomain Movement 16%

Biochemistry, Genetics and Molecular Biology

• Isoform 100%
• Exon 100%
• C-Terminus 28%
• Dynamics 14%
• Conformational Change 14%