Steroids in bacterial meningitis: Yes

Felix Benninger, Israel Steiner

Research output: Contribution to journalReview articlepeer-review

Abstract

Bacterial meningitis is an infectious condition associated with severe morbidity and mortality, even with rapid diagnosis and appropriate antibiotic therapy. Despite decrease in the rate of bacterial meningitis brought about by vaccination programs against Haemophilus influenzae type-B and Streptococcus pneumonia, the incidence of meningitis is still unacceptably high and acute treatment remains the mainstay of therapy. The infection is accompanied by intense inflammatory response, which may carry deleterious effects upon the tissue. This led to the possibility of adjuvant corticosteroid therapy, as an anti-inflammatory agent, in bacterial meningitis. The debate focuses on the rational and evidence supporting and refuting such an approach.

Original languageEnglish
Pages (from-to)339-342
Number of pages4
JournalJournal of Neural Transmission
Volume120
Issue number2
DOIs
StatePublished - Feb 2013
Externally publishedYes

Keywords

  • Bacterial
  • Meningitis
  • Steroids
  • Treatment

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