Steroid hormone hypersensitivity: Clinical presentation and management

Alek M. Itsekson, Daniel S. Seidman, Matityahu Zolti, Michael Alesker, Howard J.A. Carp

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


Hypersensitivity to estrogens and progestogens is often undiagnosed. The condition has many manifestations, including premenstrual syndrome, dysmenorrhea, and impaired fertility. Diagnosis is confirmed by skin testing for inflammatory responses to small doses of the hormone, and desensitization with small doses of the hormone is the most appropriate form of management.

Original languageEnglish
Pages (from-to)2571-2573
Number of pages3
JournalFertility and Sterility
Issue number8
StatePublished - 30 Jun 2011
Externally publishedYes


  • Hormone sensitivity
  • desensitization
  • infertility
  • premenstrual syndrome
  • skin allergy testing


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